Niacinamide

Niacinamide is a true skincare superstar and a celebrated form of vitamin B3. This water-soluble vitamin works with the natural substances in your skin to address a multitude of concerns. It is a versatile, foundational ingredient known for its ability to visibly improve skin's tone, texture, and resilience.

Natural Science

Scientifically known as nicotinamide, niacinamide is the physiologically active amide form of vitamin B3. It is an essential nutrient that our body cannot produce on its own. In skincare, it acts as a precursor to vital coenzymes, specifically NADH and NADPH.

These coenzymes are central to over 40 biochemical reactions, playing a crucial role in cellular energy production, DNA repair, and maintaining cellular health. By supporting these fundamental processes, niacinamide helps skin cells function at their best, leading to a healthier and more radiant complexion.

Benefits of Niacinamide in Skincare

Niacinamide is a multi-tasking powerhouse that offers a comprehensive approach to skin health. It addresses concerns from barrier integrity to aging, making it an invaluable addition to nearly any skincare routine for its restorative and balancing effects.

• Strengthens the Skin Barrier: It significantly boosts the production of ceramides, the lipids that form the skin's protective barrier. This is the cornerstone of niacinamide for skin barrier repair, helping skin retain moisture and defend against environmental aggressors.
• Regulates Oil and Minimizes Pores: For those seeking solutions with niacinamide for oily skin, this ingredient helps balance sebum production. By preventing excess oil from clogging pores, it can lead to a visible reduction in niacinamide and pore size.
• Evens Skin Tone: A key benefit is its effectiveness in tackling niacinamide for hyperpigmentation. It works by inhibiting the transfer of melanin pigment to skin cells, which helps fade dark spots and post-acne marks for a more uniform complexion.
• Reduces Fine Lines and Wrinkles: Niacinamide supports the production of collagen, a crucial protein for skin's structure and firmness. This action can help soften the look of niacinamide and fine lines, promoting a smoother, more youthful appearance.
• Soothes and Calms: With its potent anti-inflammatory properties, niacinamide is excellent for reducing redness and sensitivity. This makes it a go-to ingredient for those looking for solutions with niacinamide for sensitive skin or conditions like rosacea.

How Its Used in Nuebiome Products

At Nuebiome, we harness the multifaceted power of niacinamide to create formulas that deliver visible, transformative results. Its ability to support the skin microbiome and enhance overall skin health makes it a perfect fit for our biotic-infused skincare. You can experience its benefits in our Empris-Peony™ Biotic Resurfacing Night Serum.

Research

Scientific research validates niacinamide's extensive dermatological benefits. Studies published in journals like Skin Pharmacology and Physiology and the Journal of Cosmetic Dermatology show it effectively stabilizes the epidermal barrier, exhibits potent anti-inflammatory properties, and can reduce hyperpigmentation by inhibiting pigment transfer. Further evidence supports its ability to improve skin elasticity, smooth the appearance of fine lines and wrinkles, and protect the skin from environmental stressors, confirming its role as a versatile and foundational skincare ingredient.

Frequently Asked Questions about Niacinamide

What does niacinamide do for the skin?

Niacinamide is a versatile ingredient that strengthens the skin's barrier, regulates oil production to minimize pores, reduces inflammation and redness, evens out skin tone by fading dark spots, and helps smooth fine lines by boosting collagen production.

What should you never mix niacinamide with?

The old concern about mixing niacinamide with Vitamin C (L-Ascorbic Acid) is largely outdated due to modern, stable formulations. However, if you have very sensitive skin, you might consider alternating high-strength niacinamide and strong acids (like AHAs or BHAs) between morning and night routines to minimize any potential for irritation.

Is it safe to use niacinamide on face everyday?

Yes, niacinamide is very safe and well-tolerated for daily use. Most people can use it in both their morning and evening skincare routines without issue. Its supportive and calming nature makes it an excellent ingredient for consistent, long-term application.

What are the disadvantages of niacinamide on the face?

Disadvantages are rare and typically mild. Some individuals may experience temporary redness or flushing, particularly when first using a high concentration (over 10%). This is often minimal and subsides as the skin adjusts. To avoid this, start with a lower concentration and patch-test before full facial application.

Niacinamide References

Niacinamide - mechanisms of action and its topical use in dermatology.. Skin Pharmacol Physiol, 2014

Nicotinic acid/niacinamide and the skin.. J Cosmet Dermatol, Apr 2004

Cosmeceutical Aptitudes of Niacinamide: A Review.. Recent Adv Antiinfect Drug Discov, 2021